Figure 5

Variability profile of blood and LCL genomes. Variability values estimated on nearly 10,000 mitochondrial nucleotide multi-aligned sequences, available in HmtDB web site [33] are reported versus the variant positions observed in both blood and LCL samples. The trend is similar for both datasets: almost all of the variant positions display a very low variability (<0.20). Positions showing high variability, i.e. those which were common in the genomes within HmtDB, were few and represented the 25% of total shared variants between the two datasets, while the majority of non-shared variants (about 98%) displayed low variability.