Figure 2

Unrooted tree of T. brucei protein kinases. The catalytic domains of predicted functional ePKs were analyzed using MRBAYES. Bootstrap values greater than 0.95 are indicated by a dot at the node, and selected lower values are shown. No members clustered with TK or TKL kinases from human or yeast (not shown on the tree). T. brucei sequences are identified by systematic gene IDs. Selected human (Hs), S. cerevisiae (Sc) and D. melanogaster (Dm) were included to provide landmarks and these are shown in red font. Asterisks mark sequences for which the MRBAYES tree conflicted with the BLAST analysis at the group level. Kinases classified as unique through BLAST are marked with "U".