Fig. 2
From: KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily
Prediction of pathogenicity for variants uncharacterised in UniProt. a Distribution of predictions of pathogenicity in the different protein kinases; b Fraction of predictions as disease-associated and neutral; c Distribution of predictions of pathogenicity in the different groups in the taxonomy of protein kinases; d Distribution of predictions of pathogenicity respect to PFAM domains; e Distribution of the PFAM domain log odds-ratios for neutral and disease-associated variants; f Distribution of the accummulated Gene Ontology log odds-ratios (sumGOlor) for neutral and disease-associated variants