Fig. 5

Transcription factor rewiring for Module-40 genes. Here M is branch 20 from the phylogeny tree, so M={1,⋯,20}, and M ^⋆={21,⋯,23}. Branch 20 is special in that it cuts the tree at the root separating the tree into two branches: M ^⋆ is also a branch. Hence the roles of M and M ^⋆ can be switched and the red and blue colors could be reversed. Notice then that branch M ^⋆ has a wide separation between red and blue, while for the rest of the species of the tree, red and blue are closer together