Fig. 1

Distribution of HVR1 variants by DNA nt frequency. Shown are binned plots of 5681 HVR1 PhyChem variants derived from 222 patients. Y-axis denote fraction (percent) of variants with same occurrence frequency (x-axis) for: (a) nt A, (b) nt G, (c) nt C and (d) nt T. R- and C-associated variants are denoted in red and blue bars, respectively