Fig. 3

Regulatory network analysis reveals a set of immediate-early genes that are acutely responsive to NE stimulation. Integrated view of relationships between master (1) and local (2) regulators, their expression (3) and their predicted targets (4) mapped to the chromosomal context (5). Regulatory edges link the master regulators to their targets, which were colored as indicated in the figure. Up-regulated (a) and down-regulated (b) regulatory networks, based on acute responses to NE stimulation, revealed master regulators with different targets, as shown in histograms