Fig. 1

The principle of this two-way rectification. The color of expression data represent the different expression values of genes in control and test samples. The solid dot nodes represent a set of DEGs, and the diamond nodes with blue color represent those enriched pathways. The color of circle node depicts the differential expression level of the gene, the more significant the differential expression level of the gene, the closer the color of the node to red. Edge connects between a gene and a pathway means the gene is one of the annotated genes in that pathway. The thicker the edge, the closer the relationship between the gene and the pathway