Fig. 8

The details of the two-way rectification. The cycle nodes with color corresponding to the ranked genes that sorted according to the differential score, where the larger the differential score, the redder the color. Pi1 or Pi2 in a is a subset of \(P_{i1}^{\prime }\) or \(P_{i2}^{\prime }\) in b, cause only part of related genes will be found when conduct a gene list (such as DEGs- i1) into KEGG pathway enrichment, whereas \(P_{i1}^{\prime }\) or \(P_{i2}^{\prime }\) has more genes itself