Fig. 1

The three types of CRISPR-Cas systems found in B. fragilis genomes. (A) Representatives of B. fragilis CRISPR-Cas systems found in B. fragilis strain S14 (accession number: GCA_001682215.1_ASM168221v1). The figure legend indicates the CRISPR-Cas types by color where each arrow represents a gene and its orientation. While some cas genes are labeled in italicized text below the arrows, further details can be found on the companion website for this accession number. CRISPR arrays are labeled by their number of repeats in blue text. The predicted anti-repeat that is partially complementary to the CRISPR repeat in the Type II system is shown as a red triangle in the plot. (B) Prevalence of CRISPR-Cas systems among the NCBI reference genomes and Zhao2019 isolates. (C) Spacer content heterogeneity of the CRISPR arrays