Fig. 4

Mean nucleotide diversity of five Biomphalaria sudanica inbred line genomes in windows of 100 kb (0 kb stagger). Linkage groups (LG1-LG18) for B. sudanica are inferred from B. glabrata [6], showing the hypothesized chromosomal position of contigs in B. sudanica. Notable clusters of highly diverse genomic regions and genes were seen in B. sudanica linkage groups LG6, LG10 and LG16 (highlighted in turquoise and red peaks). Peaks in red represent regions containing candidate immune loci that are orthologous to some of those previously associated with Schistosoma mansoni resistance in B. glabrata (PTC1, PTC2, Catalase, BgTLR, RADres, see Supplementary Table 2)