Skip to main content

Table 4 A subset of the genes from iM line B. glabrata involved in reproductive development, gamete production, and egg or egg mass production implicated as targets of trematode-mediated castration that might serve as useful markers for this process, and as potential targets for control operations

From: Different metazoan parasites, different transcriptomic responses, with new insights on parasitic castration by digenetic trematodes in the schistosome vector snail Biomphalaria glabrata

General sexual development

 

BgiM13571

DMRTI or 1 doublesex- and mab-3-related transcription factor 2

BgiM10972

DNA-directed RNA polymerase II subunit RPB1

BgiM24147

forkhead box protein P1

BgiM03615

FOX or forkhead box protein B1-like isoform X1

BgiM00177

GATA zinc finger domain-containing protein 14

BgiM22838

GATA zinc finger domain-containing protein 15

BgiM22839

GATA zinc finger domain-containing protein 15

BgiM12852

nanos 1-like isoform X2

BgiM26970

piwi-like protein 1

BgiM03226

protein boule-like isoform X2

BgiM14501

thyrotropin-releasing hormone-degrading ectoenzyme

BgiM07364

vasa (ATP-dependent RNA helicase DHX57)

 

E3 ubiquitin-protein ligases*

 

endothelin converting enzyme 1, 2 and -like 1*

 

kelch-like proteins*

 

FMRFamides*

 

ovipostatins*

 

zinc finger proteins*

Meiosis

 

BgiM04788

meiosis-specific with OB domain-containing protein-like

BgiM02188

meiotic recombination protein REC8-like protein

BgiM12503

meiotic recombination protein SPO11-like isoform X1

Testis development/spermatogenesis

BgiM36176

cilia- and flagella-associated protein 52

BgiM27401

dynein heavy chain 8 axonemal

BgiM31883

G2/mitotic-specific cyclin-B3

BgiM29077

histone H2B.2 sperm-like

BgiM11775

kelch-like protein 10

BgiM12727

nardilysin

BgiM08071

testis-specific serine/threonine-protein kinase 2

BgiM08069

testis-specific serine/threonine-protein kinase 3

BgiM13792

tudor domain-containing protein 1*

Ovarian development/oogenesis

BgiM32459

cell division cycle protein 20

BgiM24484

MAM and LDL-receptor class A domain-containing protein 1-like isoform X2

BgiM24348

MAM and LDL-receptor class A domain-containing protein 2

BgiM12520

vitellogenin-4

 

E3 ubiquitin-protein ligases*

Egg/egg mass production

BgiM17528

bactericidal permeability-increasing protein

BgiM17527

LBP/BP1

BgiM17525

LBP/BP1.2

BgiM35341

ovulation prohormone**

BgiM20266

tyrosinase-like protein -tyr-3

BgiM12520

vitellogenin-4

BgiM28031

vitellogenin-A2

BgiM00991

yolk ferritin

  1. Note: The genes listed here were notable for the extent and/or persistence of their down-regulation following trematode infection but in some unusual cases might also be up-regulated, possibly as a means to ensure some reproductive success for the snail (forms of fecundity compensation – see text). Assignation of some of these genes to the specific categories listed should be considered provisional, as some of the genes may play roles in several aspects of reproductive physiology and there is much to be clarified with respect to their exact function and specificity
  2. *Indicates general categories for which several different genes might be involved in the response
  3. **This gene might contribute to fecundity compensation early in the course of infection in some trematode-mollusc systems
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us