Table 4 Examination of the relationship between the correlation direction of the predicted miRNA-gene pairs and their regulatory direction
From: Predicting microRNA target genes using pan-cancer correlation patterns
miRNA | Datasets | Cancer context | Regulatory direction | Sign of correlation | Gene |
|---|---|---|---|---|---|
mir-335 | GSE68742 | SARC | down | negative | CFLAR, FIGN, MSRB3, SOD3, RGS2, SGK1, PMP22 |
down | positive | CCDC3, LDB2, DZIP1, KLF2, CXCL12, NTRK3, PABPC5, RBMS3, RCBTB2, RUNX1T1 | |||
up | negative | A2M, ACTA2, DUSP3, TNFSF10, SGCB, SPARCL1, SSFA2, FAS | |||
up | positive | EGR2, JDP2, PRICKLE1, LOC728392, MATN2, LMO2 | |||
mir-335 | GSE9586 | LUAD | down | negative | CD247, DPYD, F3, LHFP, PTX3, MNDA, MT1E, MYL9, SCD5, SLFN11 |
down | positive | OSR2 | |||
up | negative | ADAM23, CALD1, CALHM2, CTTNBP2NL, DIXDC1, DUSP3, FBXL7, GCC2, GLI3, HVCN1, JAK1, MCTP1, SGCB, RHOJ, PCDHGA9 | |||
mir-192 | GSE62951 | LIHC | down | negative | E2F7, KIF2C, MTBP, NCS1, RAD54L |
up | positive | KIF4A | |||
mir-192 | GSE69990 | OV | down | negative | SERTAD2 |
down | positive | BIRC5, EZH2, PLK1 | |||
mir-26b | GSE12091 | CESC | down | positive | C1S |
mir-193b | GSE83690 | SARC | down | positive | C9orf140, CCNB2, CENPA, KIF23, KIF2C, NUSAP1, TROAP |
mir-193b | GSE25215 | PAAD | up | positive | CCNB2, CDC25C, CENPO, KIF23, KIF2C, PTTG1, TROAP, TTK |
mir-193b | GSE18510 | SKCM | up | positive | BIRC5, KIF2C |
mir-21 | GSE136665 | COAD | up | negative | ACADSB, NAP1L5 |
up | positive | AKAP11 |