Table 2 List of ten (10) hub genes identified from the protein-protein interaction (PPI) network derived using the complete set of differentially expressed genes (DEGs) in all three groups. The top 10 hub genes were generated based on their degree of connectivity matrix employed using the Cytoscape plugin (CytoHubba). Their respective expression pattern (Up-regulated or Down-regulation) derived using Log2 fold change values in each respective group were shown. Their descriptions were investigated and mentioned under the description column and functions under the function column
Genes | L_vs _H Regulation | R_vs_H Regulation | R_vs_L Regulation | Description | Function |
|---|---|---|---|---|---|
LOC408328 | Down | Down | Up | Elongation factor Tu, mitochondrial-like | Uncharacterized |
LOC410200 | Down | Down | Up | mRNA turnover protein 4 homolog | Uncharacterized |
HSC70-4 | Down | Down | Down | Heat shock protein cognate 4 | Uncharacterized |
LOC552531 | Down | Down | Down | 10Â kDa heat shock protein, mitochondrial | Uncharacterized |
HSC70-5 | Down | Down | Up | heat shock protein cognate 5 | Uncharacterized |
LOC552572 | Down | Down | Up | Eukaryotic translation initiation factor 5Â A | Uncharacterized |
LOC410620 | Up | Down | Down | Heat shock protein Hsp70Ab-like | HSP |
RPL39 | Down | Up | Up | Ribosomal protein L39 | Ribosomal protein |
LOC411351 | Down | Up | Up | Elongation factor G, mitochondrial | Uncharacterized |
HSP90 | Down | Down | Down | Heat shock protein 90 | HSP |