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Table 5 Single nucleotide polymorphisms associated with cow fertility using GBS variants

From: Validation of loci and genes associated with fertility in Holstein cows using gene-set enrichment analysis-SNP and genotype-by-sequencing

BTA (Mb)a

# SNP in Locus

Phenotypeb

Modelc

GBS

P-Value

Region Feature(s)d

1 (83.7)

2

CCR1

TBRD

Add

Add

0.04*

2.10 × 10− 11

ENSBTAG00000032217

1 (146.1)

1

TBRD

Add

2.23 × 10− 08

DIP2A

20 (46.0)

1

TBRD

Add

1.82 × 10− 06

nsv810323

  1. a Chromosome location of the locus followed by the location of the locus in megabases (Mb) as denoted in the ARS-UCD 1.2 reference genome assembly (https://www.animalgenome.org/repository/cattle/UMC_bovine_coordinates/; accessed 5 September 2023). b Cow conception rate to first service (CCR1); Number of breeding services required to achieve conception (TBRD). c Inheritance model: additive (Add), dominant (Dom), recessive (Rec). d Genomic feature that the locus/SNP are located within: gene, regulatory regions, copy number variants (CNVs), conserved regions. *FDR < 0.05