Fig. 1

Proportional-area Venn Diagrams depict unique and shared numbers of differentially expressed genes (DEG) in fetal placenta among fetal contrast groups. Each group of fetuses was contrasted with the control group. Group control (CTRL) was mock infected, viable and low virus fetus (VIA_LVF in red), viable and high virus fetus (VIA_HVF in green), meconium mild and high virus fetus (MECm_HVF in blue), and meconium severe and high virus fetus (MECs_HVF in orange). Meconium mild and low virus fetus (MECm_LVF) had no DEG and is not included). Analysis for DEG was completed in Limma and those reported were significant at P ≤ 0.05. Bubble sizes are based on relative numbers of DEG for a given contrast calculated using the Euler method