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Fig. 2 | BMC Genomics

Fig. 2

From: Altered structural and transporter-related gene expression patterns in the placenta play a role in fetal demise during Porcine reproductive and respiratory syndrome virus infection

Fig. 2

Heatmaps of log2 fold changes by gene grouping for all 86 test genes in fetal placenta for each fetal contrast group. Each group of fetuses was contrasted with the control group. Group control (CTRL) was mock infected, viable and low virus fetus (VIA_LVF), viable and high virus fetus (VIA_HVF), meconium mild and low virus fetus (MECm_LVF), meconium mild and high virus fetus (MECm_HVF), and meconium severe and high virus fetus (MECs_HVF). Each figure shows an individual gene grouping: A) actin cytoskeleton signaling, B) arachidonic acid, C) integrin signaling, D) intercellular junctions, E) transporters, and F) VEGF signaling. Note that genes within each gene grouping were sorted from high to low log2FC values in the MECs_HVF fetal group. Analyses for DEG were completed in Limma with asterisks (*) used to show significant (P ≤ 0.05) differences from CTRL. The color corresponds to a gradient of the log2FC values ranging from − 3 to + 2 with upregulated in red and downregulated in blue

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BMC Genomics

ISSN: 1471-2164

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