Fig. 2

Analysis of DMRs in bull X and Y Sperm. (A) Cluster analysis of DNA methylation data from 6 sperm samples. (B) Top: Distribution of hypermethylated regions in major functional elements of the genome. Bottom: Distribution of hypomethylated regions in major functional elements of the genome. The X-axis represented the main functional elements of the genome, and the Y-axis showed the ratio of observed to expected values. The observed/expected ratio was calculated as follows: the observed percentage (genomic elements with DMRs) was divided by the expected percentage (all genomic elements) of each genomic feature (e.g., genic, promoter) relative to the whole genome length