Fig. 1

Data processing and analysis workflow for multi-omics integration in the Uganda RSTR cohort. This analysis consisted of four major parts: (1) input feature selection, (2) creation of the MOFA factors, (3) comparison of top-weighted features on significant factors with those from other latent variable integration methods and selection of features highlighted by MOFA and at least two additional methods, (4) and factor annotation based on functional enrichment of those reduced feature lists and summary of enrichment results by gene set clustering. Created in https://BioRender.com