Table 5 Genes with high prevalence across more than one large gene set cluster in factor 4
Gene | Clusters | Dataset | Feature ID | MOFA Weight | Groupwise StatisticsA | P-value | |
|---|---|---|---|---|---|---|---|
TBI | RSTR | ||||||
SRC | F4-4, F4-26, F4-3, F4-30, F4-14 | SNP | rs12329503 | 0.529 | 00:12 | 00:04 | 0.003 |
01:03 | 01:11 | ||||||
02:00 | 02:03 | ||||||
rs6018088 | 0.493 | 00:10 | 00:04 | 0.011 | |||
01:05 | 01:08 | ||||||
02:00 | 02:06 | ||||||
rs6018148 | 0.465 | 00:10 | 00:04 | 0.018 | |||
01:05 | 01:10 | ||||||
02:00 | 02:04 | ||||||
rs6018257 | 0.662 | 00:12 | 00:04 | 0.002 | |||
01:01 | 01:10 | ||||||
02:01 | 02:04 | ||||||
HCK | F4-4, F4-3 | SNP | rs4561724 | 0.459 | 00:09 | 00:03 | 0.025 |
01:06 | 01:13 | ||||||
02:00 | 02:02 | ||||||
BLK | F4-4, F4-14 | SNP | rs2248932 | 0.558 | 00:07 | 00:04 | 0.037 |
01:08 | 01:08 | ||||||
02:00 | 02:06 | ||||||
DSCAM | F4-7, F4-5 | SNP | rs1012854 | 0.964 | 00:08 | 00:01 | < 0.001 |
01:07 | 01:07 | ||||||
02:00 | 02:10 | ||||||
rs11700509 | 0.677 | 00:08 | 00:02 | 0.031 | |||
01:04 | 01:10 | ||||||
02:03 | 02:06 | ||||||
PRKCZ | F4-19, F4-6 | SNP | rs2803310 | 0.597 | 00:10 | 00:02 | 0.002 |
01:05 | 01:10 | ||||||
02:00 | 02:06 | ||||||
VAV2 | F4-26, F4-20, F4-14 | Methylation | cg21223341 | -0.293 | 4.015 ± 0.122 | 3.554 ± 0.154 | 0.029 |
EPHB2 | F4-7, F4-19, F4-14 | Methylation | cg13102231 | -0.237 | 2.759 ± 0.101 | 2.767 ± 0.170 | 0.97 |
GNA12 | F4-30, F4-20, F4-14 | ATAC-seq | ID_chr7_2742848_2743374 | -0.112 | 2.152 ± 0.236 | 0.834 ± 0.233 | < 0.001 |