Fig. 3
From: LungGENIE: the lung gene-expression and network imputation engine
Comparison of correlation between imputed vs. observed gene expression in SUBR and GTEx across LungGENIE models
Box-and-whisker plots showing the concordance between observed lung gene expression compared with LungGENIE-imputed transcripts and directly observed transcript levels in blood. The red and blue distributions depict the concordance of expression levels between blood vs. lung tissues, and between LungGENIE-imputed vs. lung tissues, respectively, within the SUBR dataset. These distributions specifically pertain to transcripts that demonstrated significant replication compared to cross-validation performance. The green distribution depicts the corresponding accuracy of LungGENIE derived from 5-fold cross-validation within GTEx. Asterisks (*) denote FDR-adjusted statistically significant differences in group means based on pairwise t-tests. Grey points depict transcripts that were beyond the interquartile range of each group.