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Table 1 Expression of lipid metabolism-related genes in the WTgroup and fbn1+/− group

From: Identification and functional validation of a novel FBN1 variant in a Marfan syndrome family using a zebrafish model

Gene

WT-1

WT-2

WT-3

WT-mean

MU-1

MU-2

MU-2

MU-mean

P value

fosl1a

3.326

1.93

3.037

2.764

130.99

125.907

90.316

115.7

0.000910

lepb

0

0

0.124

0.041

134.995

180.088

127.848

147.6

0.000835

lepa

0.169

0.144

0

0.104

16.229

15.11

13.426

14.92

0.000054

fosl2

5.802

6.204

4.436

5.481

30.738

32.329

36.919

33.33

0.000134

irx5a

32.729

32.24

26.407

30.46

17.608

18.401

22.11

19.37

0.010763

wnt11

42.957

43.844

37.41

41.40

11.916

11.503

13.283

12.23

0.000151

ctnnb1

11.916

11.503

13.283

12.23

173.509

188.357

180.502

180.8

0.000003

tgfb1a

4.122

4.483

4.245

4.283

18.109

18.215

16.167

17.50

0.000040

tgfbr2a

1.31

1.267

0.903

1.160

9.862

12.931

8.457

10.42

0.002223