Fig. 4

Identification of differentially expressed genes in differential TADs. (a) Genes identified as differentially expressed in the liver and adipose tissue comparison group. (b) The plot regional chromosome position. The differential TAD of Bamaxiang between adipose and liver tissues where the gene NOCA2 is located (second-third panel), and chromatin states (fourth panel) and RNA-seq (last panel) in this region. the dashed lines indicate the differential positions and the RNA-seq signals in the two tissues. The bars represent the chromatin states; red represents promoters, green represents TSS-proximal transcribed regions, yellow represents enhancers, blue represents ATAC islands, and grey represents repressed regions. (c) Genes identified as differentially expressed between muscle and adipose tissue. (d) The plot regional chromosome position. The differential TAD of LargeWhite between adipose and muscle tissues where the gene BMPER is located (second-third panel), and chromatin states (fourth panel) and RNA-seq (last panel) in this region. The dashed lines indicate the differential positions and the RNA-seq signals in the two tissues. The bars represent the chromatin states; red represents promoters, green represents TSS-proximal transcribed regions, yellow represents enhancers, blue represent ATAC islands, and grey represents repressed regions. The small red rectangles mean a 50 kb resolution of TADs