Table 1 Summary of key terms. Column 1 refers to the terminology introduced in Fig. 1 and used throughout the manuscript. Column 2 gives the definition of the term
Terminology | Definition |
|---|---|
sample | Tissue slice (from a tissue block) or cell mixture from tissue |
donor | Subject-level identifier for source of tissue |
bulk sample | Tissue sample containing mixture of cells across K cell types (Y) |
Cell type reference matrix | Matrix containing cell type-specific gene expression for G genes across K cell types (Z) |
Cell size factors | vector of cell sizes of K cell types (S) |
Cell composition | vector of the proportion of K cell types in a given bulk sample (P) |
RMSE | Square root of the mean of squared errors |