Fig. 2

Histogram and time-course analysis of Spearman correlation coefficients between RNA-Seq and NanoString gene expression data. The panel (a) shows the distribution of Spearman correlation coefficients across 62 samples, with a mean of 0.83, a median of 0.85, and most values concentrated between 0.8 and 0.9. The panel (b) illustrates the Spearman correlation coefficients over Days Post Infection (DPI) for four distinct groups of NHPs, with each line representing an individual NHP. (c) Gradual increase in Spearman correlation coefficient for sample NHP-5-3 as genes are removed using the Reverse Gene Removal (RGR) method