Fig. 3

Transcripts associated with variation in metabolite abundance via transcriptome-wide association. Each circle’s position on the x-axis indicates the annotated location of a gene model on the maize genome and its position indicates the statistical significance of the link between variation in the expression of the primary transcript of that gene model and variation in the abundance of a specific metabolite indicated by the color of the dot. Results are shown only for the three metabolites where the significance of at least one transcript exceeded \(-\log _{10}(2.03 \times 10^{-6})\), corresponding to the Bonferroni-corrected p-value of 0.05 after correcting for the 24,585 transcripts tested. This threshold p-value is indicated via a horizontal dashed red line. The names of either the proteins encoded by genes above the threshold, or gene model IDs are labeled. Two separate genes, both encoding Cu(2+)-exporting ATPase (Cu(2+)-exporting ATPase) were associated with variation in the abundance of glycerol 1-phosphate, one of which was also associated with variation of L-glutamic acid. Alternating color horizontal lines along the x-axis indicate the start and end of each maize chromosome