Fig. 4

Functional enrichment of the differential genes and metabolites. KEGG pathway enrichment of DEGs in blood (A) and muscles (B). The dot size represents the number of differentially expressed genes in that pathway, and the dot color represents the p value. (C) Functional enrichment bar chart of detected metabolites in positive and negative ion mode categorized into cellular process, environmental information processing, genetic information processing, metabolism, and organismal systems