In-silico analysis of deleterious non-synonymous SNPs in the human AVPR1a gene linked to autism

BMC Genomics

Table 1 Risky nsSNPs screened by SIFT, Polyphen, and PROVEAN

Variant ID	Nucleotides	AA Variations	SIFT	Prediction	Polyphen	Prediction	PROVEAN	Prediction
Variant ID	Nucleotides	AA Variations	Score	Prediction	Score	Prediction	Score	Prediction
rs1260022270	C/T	R85H	0	De	1	P D	−4.557	De
rs1267958616	C/T	D202 N	0	De	1	P D	−4.955	De
rs1321994497	T/C	E54G	0	De	1	P D	−6.152	De
rs1325662981	T/G	H92P	0	De	1	P D	−9.126	De
rs1337643184	C/A	D148Y	0	De	1	P D	−8.744	De
rs1338176647	A/C	C203G	0	De	1	P D	−11.893	De
rs1369668995	C/T	V297M	0	De	1	P D	−2.867	De
rs1377891669	T/A	D148 V	0	De	1	P D	−8.744	De
rs1417441306	C/T	S182 N	0	De	1	P D	−2.931	De
rs1424280726	T/A	Q108L	0	De	1	P D	−6.529	De
rs1440280008	G/A	R149 C	0	De	1	P D	−7.772	De
rs1449556252	C/A	G212 V	0	De	1	P D	−8.918	De
rs369710823	A/G	M145 T	0	De	1	P D	−5.810	De
rs376518166	C/T	G212S	0	De	1	P D	−5.946	De
rs745458336	T/G	Y140S	0	De	1	P D	−8.344	De
rs748572296	A/C	F207 V	0	De	1	P D	−6.937	De
rs754449459	T/A	Q108H	0	De	1	P D	−4.663	De
rs758567125	A/C	W219G	0	De	1	P D	−12.884	De
rs767540299	G/A	R284 W	0	De	1	P D	−7.070	De
rs772227542	G/A	L93 F	0	De	1	P D	−3.650	De
rs773269527	G/C	P156R	0	De	1	P D	−8.794	De
rs776488571	A/C	F136 C	0	De	1	P D	−7.712	De
rs780705756	G/A	P107L	0	De	1	P D	−9.216	De

ISSN: 1471-2164