Table 5 Conservation analysis results of identified 23 mutants evaluated by predict protein server
From: In-silico analysis of deleterious non-synonymous SNPs in the human AVPR1a gene linked to autism
Variant ID | AA substitution | Predict Protein | |
|---|---|---|---|
Score | Prediction | ||
rs1260022270 | R85H | 7–9 | Highly conserved |
rs1267958616 | D202 N | 7–9 | Highly conserved |
rs1321994497 | E54G | 7–9 | Highly conserved |
rs1325662981 | H92P | 7–9 | Highly conserved |
rs1337643184 | D148Y | 7–9 | Highly conserved |
rs1338176647 | C203G | 7–9 | Highly conserved |
rs1369668995 | V297M | 7–9 | Highly conserved |
rs1377891669 | D148 V | 7–9 | Highly conserved |
rs1417441306 | S182 N | 7–9 | Highly conserved |
rs1424280726 | Q108L | 7–9 | Highly conserved |
rs1440280008 | R149 C | 7–9 | Highly conserved |
rs1449556252 | G212 V | 7–9 | Highly conserved |
rs369710823 | M145 T | 7–9 | Highly conserved |
rs376518166 | G212S | 7–9 | Highly conserved |
rs745458336 | Y140S | 7–9 | Highly conserved |
rs748572296 | F207 V | 7–9 | Highly conserved |
rs754449459 | Q108H | 7–9 | Highly conserved |
rs758567125 | W219G | 7–9 | Highly conserved |
rs767540299 | R284 W | 7–9 | Highly conserved |
rs772227542 | L93 F | 7–9 | Highly conserved |
rs773269527 | P156R | 7–9 | Highly conserved |
rs776488571 | F136 C | 7–9 | Highly conserved |
rs780705756 | P107L | 7–9 | Highly conserved |