Fig. 3

Characterization and comparison of the transcriptional profiles. (a) PCA plot. (b) Scatter diagram demonstrating the DEGs for two different comparison schemes (SAS vs. SMS and SAW vs. SAS, the latter is considered the reference group). The FDR < 0.01 is indicated in red, while the FDR ≥ 0.01 is indicated in blue. The networks showed the core pathways of (c) SAS vs. SMS and (d) SAW vs. SAS. Each dot represented a pathway, and only the significant pathways are shown. The more DEGs enriched within the pathway, the larger the dot. Also, the color of the dot reflected the p-value. Only the names and map IDs of critical pathways are shown in the map