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Fig. 7 | BMC Genomics

Fig. 7

From: The whole genome analysis of the wild-type and attenuated orf virus reveals that ORF022 facilitates viral replication

Fig. 7

Expression of inflammation-associated genes and viral genes. A: Heat map of immune and TNF signaling pathway-related genes from pcDNA3.1-022 group and pcDNA3.1-022 + FX0910 group. (B-C): Real-time PCR of immune and TNF signaling pathway related genes mRNA from pcDNA3.1-022 group (B) and pcDNA3.1-022 + FX0910 group (C). (D): The ratio of reads in the read count (group pcDNA3.1-022 + FX0910) that match FX0910, indexed by FX0910. (E): Volcano plot of DEGs in ORFV. (F): Spearman correlation analysis of ORFV genes expression (FPKM) with an absolute value of correlation coefficient greater than 0.9 with the ORF022. Red indicates a positive correlation, and blue indicates a negative correlation. (*, P < 0.05, **, P < 0.01, ***, P < 0.001, ****, P < 0.0001)

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