Fig. 4
From: Molecular regulation of whole genome DNA methylation in heat stress response of dairy cows
Identification of key DMRs and DMGs in promoter in dairy cows under heat stress (A) The volcano plot of DEGs; B Venn diagram of promoter DMGs and DEGs; C The methylation levels of DMRs in the promoters of GNAS, DNLZ, and SMAD5; D The expression levels of GNAS, DNLZ, and SMAD5 using TPM (number of transcripts per million reads). E PPI Network interaction of DMEGs with negative regulation of expression by promoter methylation. Note: In (C) and (D), arrows indicate the direction of change, upward arrows indicate an increase, and downward arrows indicate a decrease in summer expression; *** FDR < 0.001