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  1. Gene mining is crucial for understanding the regulatory mechanisms underlying complex biological processes, particularly in plants responding to environmental conditions. Traditional machine learning methods, ...

    Authors: Kerui Huang, Jianhong Tian, Lei Sun, Haoliang Hu, Xuebin Huang, Shiqi Zhou, Aihua Deng, Zhibo Zhou, Ming Jiang, Guiwu Li, Peng Xie, Yun Wang and Xiaocheng Jiang
    Citation: BMC Genomics 2025 26:259
  2. FLOWERING LOCUS D (FD) is a basic leucine zipper (bZIP) transcription factor known to be crucial in vernalization, flowering, and stress response across a variety of plants, including biennial and winter annua...

    Authors: Wenjie Kan, Yameng Gao, Yan Zhu, Ziqi Wang, Zhu Yang, Yuan Cheng, Jianjun Guo, Dacheng Wang, Caiguo Tang and Lifang Wu
    Citation: BMC Genomics 2025 26:255
  3. Understanding the dark genome is a priority task following the complete sequencing of the human genome. Short open reading frames (sORFs) are a group of largely unexplored elements of the dark genome with the ...

    Authors: Martin Danner, Matthias Begemann, Florian Kraft, Miriam Elbracht, Ingo Kurth and Jeremias Krause
    Citation: BMC Genomics 2025 26:254
  4. Fragaria iinumae, a diploid progenitor species of octoploid strawberries, likely occupies a basal position within the genus Fragaria. In this study, we report a near-complete genome assembly of F. iinumae v2.0, t...

    Authors: Haiyuan Du, Yiying He, Maoxian Chen, Xu Zheng, Daping Gui, Jixing Tang, Yu Fang, Yiwei Huang, Hong Wan, Jiwei Ruan, Xin Jin and Andan Zhu
    Citation: BMC Genomics 2025 26:253
  5. Chenopodium quinoa Willd (Quinoa) is highly tolerant to drought, cold, and salt stress. Gene editing technology development, and research on quinoa’s drought resistance have attracted much attention. The transcri...

    Authors: Dongfang Zhang, Xiaolin Zhu, Xuefen Du, Xian Wang, Baoqiang Wang and Xiaohong Wei
    Citation: BMC Genomics 2025 26:252
  6. Echinacanthus longipes is an endemic species in the Sino-Vietnamese karst flora in the family Acanthaceae. It displays distinctive environmental adaptation characteristics in karst regions. Although it provides a...

    Authors: Chunming Gao, Shu Wang, Yusong Huang and Yunfei Deng
    Citation: BMC Genomics 2025 26:251
  7. Reproduction traits are crucial for livestock breeding and represent key economic indicators in the domestic goat (Capra hircus) industry. The oviduct, a critical organ in female mammals, plays a pivotal role in ...

    Authors: Qingqing Liu, Zhipeng Sun, Yufang Liu, Xiaoyun He, Chunhuan Ren, Xiangyu Wang, Ran Di, Yongju Zhao, Zijun Zhang and Mingxing Chu
    Citation: BMC Genomics 2025 26:250
  8. Non-coding RNAs (ncRNAs) serve as crucial regulatory elements in the process of adipogenesis in animals; however, the specific roles and interrelationships of ncRNAs in bovine fat deposition remain poorly unde...

    Authors: Yuxin Zhou, Wanping Ren, Wei Shao, Yu Gao, Kangyu Yao, Min Yang, Xinyu Zhang, Yiran Wang, Fengming Li and Liang Yang
    Citation: BMC Genomics 2025 26:249
  9. Bacteria from the genus Polaromonas are dominant phylotypes found in a variety of low-temperature environments in polar regions. The diversity and biogeographic distribution of Polaromonas have been largely expan...

    Authors: Yuntong Du, Changhua He, Karen G. Lloyd, Tatiana A. Vishnivetskaya, Hongpeng Cui, Bing Li, Da Gong, Xiaopeng Fan, Dayi Zhang, Hongchen Jiang and Renxing Liang
    Citation: BMC Genomics 2025 26:248
  10. Advancing our knowledge of vector species genomes is a key step in our battle against the spread of diseases. Biting midges of the genus Culicoides are vectors of arboviruses that significantly affect livestock w...

    Authors: Jessica Castellanos-Labarcena, Yoamel Milián-García, Tyler A. Elliott, Dirk Steinke, Robert Hanner and Sarah J. Adamowicz
    Citation: BMC Genomics 2025 26:247
  11. Drought is a major abiotic stress affecting maize development and growth. Unravelling the molecular mechanisms underlying maize drought tolerance and enhancing the drought tolerance of maize is of great import...

    Authors: Dongmei Wang, Xuyang Liu, Guanhua He, Kailiang Wang, Yongxiang Li, Honghui Guan, Tianyu Wang, Dengfeng Zhang, Chunhui Li and Yu Li
    Citation: BMC Genomics 2025 26:246
  12. RNA sequencing (RNA-seq) is a powerful tool for transcriptome profiling, enabling integrative studies of expression quantitative trait loci (eQTL). As it identifies fewer genetic variants than DNA sequencing (...

    Authors: Kaixuan Guo, Zhanming Zhong, Haonan Zeng, Changliang Zhang, Teddy Tinashe Chitotombe, Jinyan Teng, Yahui Gao and Zhe Zhang
    Citation: BMC Genomics 2025 26:245
  13. Aureobasidium pullulans is a yeast-like fungus known for its commercial biomanufacturing of pullulan. This study explores the genome of A. pullulans NRRL 62031, highlighting its biosynthetic potential, metabolic ...

    Authors: Difan Xiao, Marielle Driller, Karla Stein, Lars M. Blank and Till Tiso
    Citation: BMC Genomics 2025 26:244
  14. Photoperiod is one of the important factors affecting seasonal estrus of sheep. The importance of the uterus to reproduction is self-evident. However, the uterine molecular mechanisms involved in photoperiodic...

    Authors: Fan Yang, Jiannan Liu, Yongfu La, Ran Di, Xiaoyun He, Pingqing Wang, Yufang Liu and Mingxing Chu
    Citation: BMC Genomics 2025 26:243
  15. Myopia development is commonly assessed by an increase in axial length, which may lead to high myopia and visual impairment. This study aims to identify potential biomarkers and signaling pathways in the scler...

    Authors: He-Yan Li, Xu-Han Shi, Li Dong, Chu-Yao Yu, Yi-Tong Li, Rui-Heng Zhang, Wen-Da Zhou, Hao-Tian Wu, Jost. B. Jonas and Wen-Bin Wei
    Citation: BMC Genomics 2025 26:242
  16. Sweet sorghum (Sorghum bicolor Moench) seedling emergence and growth are significantly impeded by physical soil crusts (PSCs) in saline-alkaline soils. Abscisic acid (ABA) is a potent seed priming agent known for...

    Authors: Jianfeng Yang, Wenlan Zhang, Tianyu Wang, Jiawei Xu, Jinjing Wang, Jiahao Huang, Yingpeng Sun, Yu Ni and Yanjun Guo
    Citation: BMC Genomics 2025 26:241
  17. To solve the problem of an insufficient supply of dairy products in Tibet, work has been carried out to improve native dairy cattle and introduce purebred dairy cattle from low-altitude areas. The harsh enviro...

    Authors: Shangzhen Huang, Longgang Ma, Bin Li, Jinhuan Dou, Qing Xu and Yachun Wang
    Citation: BMC Genomics 2025 26:240
  18. Gaeumannomyces tritici is responsible for take-all disease, one of the most important wheat root threats worldwide. High-quality annotated genome resources are sorely lacking for this pathogen, as well as for th...

    Authors: Rowena Hill, Michelle Grey, Mariano Olivera Fedi, Daniel Smith, Gail Canning, Sabrina J. Ward, Naomi Irish, Jade Smith, Vanessa E. McMillan, Jess Hammond, Sarah-Jane Osborne, Gillian Reynolds, Ellie Smith, Tania Chancellor, David Swarbreck, Neil Hall…
    Citation: BMC Genomics 2025 26:239
  19. The Chinese giant salamander (CGS), Andrias davidianus, the largest living amphibian, is of significant conservation importance for its wild populations and serves as a valuable economic species in aquaculture. G...

    Authors: Shijun Yang, Xinlin Wang, Han Yang, Fan Yan, Lishan Xu, Zhijie Jian, Guangxiang Zhu and Qin Wang
    Citation: BMC Genomics 2025 26:238
  20. Genome-wide association studies (GWAS) are rapidly advancing due to the improved resolution and completeness provided by Telomere-to-Telomere (T2T) and pangenome assemblies. While recent advancements in GWAS m...

    Authors: Jyoti Sharma, Vaishnavi Jangale, Rajveer Singh Shekhawat and Pankaj Yadav
    Citation: BMC Genomics 2025 26:237
  21. Oocyte maturation is a critical process responsible for supporting preimplantation embryo development and full development to term. Understanding oocyte gene expression is relevant given the unique molecular m...

    Authors: Naru Zhou, Xin Wang, Yi Xia, Zongliang Liu, Lei Luo, Rentao Jin, Xianhong Tong, Zhenhu Shi, Zhichao Wang, Heming Sui, Yangyang Ma, Yunsheng Li, Zubing Cao and Yunhai Zhang
    Citation: BMC Genomics 2025 26:236
  22. Dairy goats, a livestock species with a long history of milk production, are essential for the economic advancement of nations, particularly in regions experiencing growth. In this study, we gathered whole-gen...

    Authors: Weifeng Peng, Yiyuan Zhang, Lei Gao, Shuping Wang, Mengting Liu, Enrui Sun, Kaixin Lu, Yunxia Zhang, Bing Li, Guoyin Li, Jingya Cao, Mingsheng Yang, Yanfeng Guo, Mengyun Wang, Yuming Zhang, Zihan Wang…
    Citation: BMC Genomics 2025 26:234
  23. Intramuscular fat (IMF) not only directly affects the tenderness, juiciness, and overall flavour of meat but also plays a significant role in influencing consumer preferences for pork. Therefore, exploring key...

    Authors: Wenqiang Li, Suozhou Yang, Huixin Liu, Zhi Cao, Fei Xu, Chao Ning, Qin Zhang, Dan Wang and Hui Tang
    Citation: BMC Genomics 2025 26:233
  24. The regulation of chromatin accessibility is essential in eukaryotic cells as one of several mechanisms that ensure gene activation occurs at appropriate times and in appropriate cell types. Accordingly, mutat...

    Authors: Prince Verma, John M. Allen, Alejandro Sánchez Alvarado and Elizabeth M. Duncan
    Citation: BMC Genomics 2025 26:232
  25. Water spinach (Ipomoea aquatica Forsk.) is an important leaf vegetable affected by salt stress, however, little is known about its salt adaption mechanism. Here, we integrated physiomics, ionomics, transcriptomic...

    Authors: Zhenqin Li, Long Cheng, Sitong Li, Guangcai Liu, Sijia Liu, Duo Xu, Rongchao Yang, Feng Feng, Junning Wang and Chao Zheng
    Citation: BMC Genomics 2025 26:231
  26. Changing ocean temperatures are already causing declines in populations of marine organisms. Predicting the capacity of organisms to adjust to the pressures posed by climate change is a topic of much current r...

    Authors: Sharon E. Hook, Ryan J. Farr, Jenny Su, Alistair J. Hobday, Catherine Wingate, Lindsey Woolley and Luke Pilmer
    Citation: BMC Genomics 2025 26:230
  27. Space travel is a growing area of interest and includes initiatives such as NASA’s Moon-to-Mars Mission. Reports on the cardiovascular effects of space travel reveal changes in morphology, metabolism, and func...

    Authors: Alicia L. Veliz, Lorelei Hughes, Delia Carrillo, Michael J. Pecaut and Mary Kearns-Jonker
    Citation: BMC Genomics 2025 26:229
  28. The brine shrimp Artemia, a crustacean adapted to the extreme conditions of hypersaline environments, comprises nine regionally distributed sexual species scattered (island-like) over heterogeneous environments a...

    Authors: Alireza Asem, Chaojie Yang, Stephanie De Vos, Farnaz Mahmoudi, Lidong Xia, Chun-Yang Shen, Francisco Hontoria, D. Christopher Rogers and Gonzalo Gajardo
    Citation: BMC Genomics 2025 26:228
  29. Few cohorts have study populations large enough to conduct molecular analysis of ex vivo lung tissue for genomic analyses. Transcriptome imputation is a non-invasive alternative with many potential applications. ...

    Authors: Auyon J. Ghosh, Liam P. Coyne, Sanchit Panda, Aravind A. Menon, Matthew Moll, Michael A. Archer, Jason Wallen, Frank A. Middleton, Craig P. Hersh, Stephen J. Glatt and Jonathan L. Hess
    Citation: BMC Genomics 2025 26:227
  30. Cell differentiation during development is orchestrated by precisely coordinated gene expression programs. While some regulatory mechanisms are well understood, there is a significant room to explore unresolve...

    Authors: Rubens Gomes-Júnior, Cintia Delai da Silva Horinouchi, Aruana Fagundes Fiuza Hansel-Fröse, Annanda Lyra Ribeiro, Isabela Tiemy Pereira, Lucia Spangenberg and Bruno Dallagiovanna
    Citation: BMC Genomics 2025 26:225
  31. Peanut (Arachis hypogaea L.) is a vital global crop, frequently threatened by both abiotic and biotic stresses. Among the most damaging biotic stresses is Tomato spotted wilt virus (TSWV), which causes peanut spo...

    Authors: Dongliang Wu, Chuanzhi Zhao, Walid Korani, Ethan A. Thompson, Hui Wang, Gaurav Agarwal, Jake C. Fountain, Albert Culbreath, C. Corley Holbrook, Xingjun Wang, Josh P. Clevenger and Baozhu Guo
    Citation: BMC Genomics 2025 26:224
  32. Cotton fiber development relies on complex and intricate biological processes to transform newly differentiated fiber initials into the mature, extravagantly elongated cellulosic cells that are the foundation ...

    Authors: Corrinne E. Grover, Josef J. Jareczek, Sivakumar Swaminathan, Youngwoo Lee, Alexander H. Howell, Heena Rani, Mark A. Arick II, Alexis G. Leach, Emma R. Miller, Pengcheng Yang, Guanjing Hu, Xianpeng Xiong, Eileen L. Mallery, Daniel G. Peterson, Jun Xie, Candace H. Haigler…
    Citation: BMC Genomics 2025 26:221
  33. In the Ist millennium BC bearers of the Scythian-type nomadic cultures inhabited the steppes of Eurasia, from Northern China to the Carpathians. According to archaeological data, the origin of nomadic life style ...

    Authors: Artem Nedoluzhko, Ekaterina Vergasova, Fedor Sharko, Natalia Agapitova, Dmitry Kharitonov, Xenia Sukhanova, Olga Pushkina, Svetlana Pankova, Natalia Slobodova, Eugenia Boulygina, Nikolay Plotnikov, Anna Kim, Evgeniia Uchaneva, Nadezhda Pogodina, Anna Ilinskaya, Alexander Rakitko…
    Citation: BMC Genomics 2025 26:220
  34. Livestock, particularly cattle, are crucial for biotechnology fields, such as genetic breeding, infectious diseases, bioreactors, and specific disease models. However, genetic engineering in cattle has lagged ...

    Authors: Dong-Hyeok Kwon, Gyeong-Min Gim, Soo-Young Yum, Kyeong-Hyeon Eom, Song-Jeon Lee, Sang-Eun Han, Hee-Soo Kim, Hyeong-Jong Kim, Woo-Sung Lee, Woo-Jae Choi, Ji-Hyun Lee, Do-Yoon Kim, Dae-Jin Jung, Dae-Hyun Kim, Jun-Koo Yi, Byeong-Ho Moon…
    Citation: BMC Genomics 2025 26:217
  35. Yunnan Province, located in Southwestern China, the intricate geography, variable climate, and abundant vegetation of the region have collectively contributed to shaping the distinctive germplasm characteristi...

    Authors: Xiwen Guan, Weixuan Xiang, Kaixing Qu, Zulfiqar Ahmed, Jianyong Liu, Ming Cai, Jicai Zhang, Ningbo Chen, Chuzhao Lei and Bizhi Huang
    Citation: BMC Genomics 2025 26:216
  36. Integrating germplasm populations genotyped by different genotyping platforms via genotype imputation is a way to utilize accumulated genetic resources. In this study, we used 278 canola samples genotyped via ...

    Authors: Huanhuan Zhao, Iona M MacLeod, Gabriel Keeble-Gagnere, Denise M Barbulescu, Josquin F Tibbits, Sukhjiwan Kaur and Matthew Hayden
    Citation: BMC Genomics 2025 26:215
  37. The present study was undertaken to elucidate the population structure and differentiation of Indian yak from Chinese and wild cohorts on genome-wide scale by identifying the selection sweeps and genomic basis...

    Authors: Sheikh Firdous Ahmad, Munish Gangwar, Amit Kumar, Amod Kumar, Mahesh Shivanand Dige, Girish Kumar Jha, Gyanendra Kumar Gaur and Triveni Dutt
    Citation: BMC Genomics 2025 26:214
  38. The cysteine-rich receptor-like kinases (CRKs) family in plants have been reported to perform multiple functions against various stresses. However, the CRK family in bottle gourd (Lagenaria siceraria) has not bee...

    Authors: Preetinanda Sahoo, Ikram Ullah, Debarpita Sahoo, Chirasmita Bose, Muhammad Amir Zia, Sumaira Salahuddin Lodhi, Mahmoud F. Seleiman, Nawab Ali, Gagan Kumar, Suhail Asad and Satyabrata Nanda
    Citation: BMC Genomics 2025 26:213
  39. Tail fat is important for fat-tailed or fat-rumped sheep to survive in harsh environments. However, the molecular mechanism underlying tail fat deposition in sheep remains unclear. In this study, we comprehens...

    Authors: Yujing Xie, Xin Li, Huili Liang, Mingxing Chu, Guiling Cao and Yunliang Jiang
    Citation: BMC Genomics 2025 26:212
  40. Avian β-defensins (AvBDs) represent a key family of antimicrobial host defense peptides in birds. Accumulating evidence suggests that the evolutionary trajectory of β-defensin genes is specific to the gene, ti...

    Authors: Xiaoqin Xu, Yi Jian, Lijing Huang, Wei Luo, Bangyuan Wu, Shaohua Feng, Caiquan Zhou and Long Zhang
    Citation: BMC Genomics 2025 26:211
  41. Substance Use Disorder (SUD) is a severe global problem that is influenced by both environmental and genetic factors. The genetic etiology of addiction can be complex and overlapping. This study aimed to inves...

    Authors: Laith AL-Eitan, Ahmad Mihyar and Mansour Alghamdi
    Citation: BMC Genomics 2025 26:210
  42. Porcine parvoviruses (PPVs) are widespread worldwide in the swine population. PPV1 is a significant infectious agent in pig production, causing porcine reproductive failure. The pathogenic potential of novel P...

    Authors: Alina Komina, Nikita Krasnikov, Maria Simakova, Valentina Rykova, Elena Zhukova, Alexander Bulgakov and Anton Yuzhakov
    Citation: BMC Genomics 2025 26:209
  43. Leaf abscission of Cyclocarya paliurus stem segments in vitro is very serious, and more than 90% of the leaves gradually fall off with prolonged culture time, which hinders breeding. This study investigated the m...

    Authors: Gaoyin Wu, Zhongcheng Peng, Qiuying Li, Xiang Zhang, Shuanggui Geng, Shuang Wang, Enrong Lu, Yingying Liu, Congjun Yuan, Xiaoli Wei and Yingliang Liu
    Citation: BMC Genomics 2025 26:208

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