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  1. The basic helix-loop-helix (bHLH) transcription factors are involved in the biosynthesis of various secondary metabolites. However, genome-wide studies on the bHLH gene family in ferns and their role in lignin bi...

    Authors: Xiong Huang, Jiangtao Fan, Cai Liu, Peiyun Wang, Hongfei Li, Gang Wang and Xiaohong Chen
    Citation: BMC Genomics 2025 26:357
    Content type: Research Published on:

  2. Rapid turnaround time for a third-field resolution deceased donor human leukocyte antigen (HLA) typing is critical to improve organ transplantation outcomes. Third generation DNA sequencing platforms such as O...

    Authors: Jalal Siddiqui, Rohita Sinha, James Grantham, Ronnie LaCombe, Judith R. Alonzo, Scott Cowden and Steven Kleiboeker
    Citation: BMC Genomics 2025 26:356
    Content type: Research Published on:

  3. The bacterium Myxococcus xanthus provides an important multicellular model for understanding stress responses. The regulatory proteins CsgA, FruA, and MrpC are essential to survive prolonged starvation by forming...

    Authors: Mark A. Farrugia, Ramya Rajagopalan and Lee Kroos
    Citation: BMC Genomics 2025 26:355
    Content type: Research Published on:

  4. Ethiopian mustard (Brassica carinata (A) Braun) is a promising oilseed crop with the potential for sustainable biofuel and bio-industrial applications. Despite the presence of diverse germplasms in Ethiopia, thei...

    Authors: Yirssaw Demeke Ambaw, Andargachew Gedebo Abitea and Temesgen Magule Olango
    Citation: BMC Genomics 2025 26:354
    Content type: Research Published on:

  5. Although advances in metagenomics, viral diversity and non-retroviral endogenous viral elements (EVEs) in wheat aphids remain underexplored. By analyzing 470 publicly available datasets and one laboratory-gene...

    Authors: Ke-Hui Feng, Yu-Hua Qi, Zhuang-Xin Ye, Ting Li, Gao-Yang Jiao, Chuan-Xi Zhang, Jian-Ping Chen, Gang Lu and Jun-Min Li
    Citation: BMC Genomics 2025 26:353
    Content type: Research Published on:

  6. Alcohol dehydrogenase has been studied in regulation of fungal growth and development, stress response and pathogenesis, but its function in T. asahii remains unexplored. In this study, we analyzed the ADH gene f...

    Authors: Zhen Liu, Xiaoping Ma, Xiangwen Zeng, Zhiguo Li, Ruiguo Liu, Rongyan Luo, Weichen Wang, Muhammad Salman Tahir, Chengdong Wang and Yu Gu
    Citation: BMC Genomics 2025 26:352
    Content type: Research Published on:

  7. Producing high-quality beef with enhanced muscle composition and reduced fat content is critical for meeting consumer preferences and supporting a balanced diet. Given the substantial variability in beef quali...

    Authors: Lin Han, Runqi Fu, Chunjia Jin, Huan Gao, Binlong Fu, Qian Li, Ye Yu, Min Qi, Jiawei Zhang, Shengyong Mao and Jing Leng
    Citation: BMC Genomics 2025 26:351
    Content type: Research Published on:

  9. The Yunshang Black Goat, a distinguished meat goat breed native to China, is renowned for its superior reproductive capabilities. Despite this, there is considerable phenotypic variability within the breed. Du...

    Authors: Xiaolong Du, Yufang Liu, Xiaoyun He, Lin Tao, Meiying Fang and Mingxing Chu
    Citation: BMC Genomics 2025 26:349
    Content type: Research Published on:

  10. Tyrosine is a prerequisite for melanin biosynthesis and plays a crucial role in the growth and development of melanocytes, but the underlying mechanism is still unclear. In our previous research, we added 10− 9-1...

    Authors: Zhiyuan Zhang, Pengwei Zhang, Fumin He, Yingdong Hou, Xiaowen Geng, Ruilong Xu, Ruiting Li, Yadong Tian, Wenting Li, Guirong Sun, Ruirui Jiang, Xiaojun Liu, Ruili Han, Guoxi Li, Xiangtao Kang and Donghua Li
    Citation: BMC Genomics 2025 26:348
    Content type: Research Published on:

  11. Differentiation of fibroblasts into myofibroblasts is necessary for wound healing, but excessive myofibroblast presence and persistence can result in scarring. Treatment for scarring is limited largely due to ...

    Authors: Michelle Bretl, Lingxin Cheng, Christina Kendziorski and Susan L. Thibeault
    Citation: BMC Genomics 2025 26:347
    Content type: Research Published on:

  12. The CYP450 family members have been extensively studied in plants, where they play essential roles in metabolism, responses to biotic and abiotic stresses, and the regulation of growth and development. However...

    Authors: Xun Liu, Xinmin Liang, Jing Han, Yuqin Cui, Mengting Lei, Bo Wang, Dinghong Jia, Weihong Peng and Xiaolan He
    Citation: BMC Genomics 2025 26:346
    Content type: Research Published on:

  13. Bats possess a uniquely adapted immune system that enables them to live with viral infections without the expected maladies. The molecular basis and regulation of bats’ immune response is still not fully under...

    Authors: Sebastien Riquier, Samuel Carthy, Graham M. Hughes, Frederic Touzalin, Wilfried Haerty, Zixia Huang and Emma C. Teeling
    Citation: BMC Genomics 2025 26:345
    Content type: Research Published on:

  14. Polymyxins are critical in treating multidrug-resistant Gram-negative bacteria infections, yet their overuse has spurred the emergence of polymyxin-resistant pathogens globally. This study aims to analyze the ...

    Authors: Yu Yang, Wenhong Liu, Zanzan Zhao, Kexin Guo, Xinrui Wang, Zhenghao Lou, Xiaolu Yang, Lu Gong, Kun Wang, Xiaojing Liu, Hao Xu, Qiyu Liu, Beiwen Zheng and Xiawei Jiang
    Citation: BMC Genomics 2025 26:344
    Content type: Research Published on:

  15. As a key genus in Zingiberaceae, Curcuma is widely studied for its taxonomic diversity, the presence of bioactive curcuminoids and volatile oils, and its extensive applications in traditional medicine and economi...

    Authors: Heng Liang, Jiabin Deng, Yidan Wang, Gang Gao and Ruiwu Yang
    Citation: BMC Genomics 2025 26:343
    Content type: Research Published on:

  16. Chromosomes of species exhibit a variety of high-dimensional organizational features, and chromatin loops, which are fundamental structures in the three-dimensional (3D) structure of the genome. Chromatin loop...

    Authors: Junfeng Wang, Lili Wu, Jingjing Wei, Chaokun Yan, Huimin Luo, Junwei Luo and Fei Guo
    Citation: BMC Genomics 2025 26:342
    Content type: Research Published on:

  17. Mammalian T cell receptor (TCR) beta-chain (TRB) V-D-J rearrangement mainly follows the “12/23 rule”, and the “D-J rearrangement preceding the V-(D-J) rearrangement”. Owing to the physical position of the D-J-...

    Authors: Yingjie Wu, Fengli Wu, Jun Li, Hao Zhou, Long Ma and Xinsheng Yao
    Citation: BMC Genomics 2025 26:341
    Content type: Research Published on:

  18. Plastids have highly conserved genomes in most land plants. However, in several families, plastid genomes exhibit high rates of nucleotide substitution and structural rearrangements among species. This elevate...

    Authors: Alfredo López-Caamal, Tyler Gandee, Laura F. Galloway and Karen B. Barnard-Kubow
    Citation: BMC Genomics 2025 26:340
    Content type: Research Published on:

  19. Oocyte competence for early embryo development relies on intercellular communication between the maturing oocyte and preovulatory follicle. Preovulatory follicle maturity, as indicated by serum estradiol conce...

    Authors: Allyson E. Stokes, Hannah M. Clark, J. Lannett Edwards, Rebecca R. Payton, Jon E. Beever, Trevor F. Freeman, Emma A. Hessock, F. Neal Schrick and Sarah E. Moorey
    Citation: BMC Genomics 2025 26:339
    Content type: Research Published on:

  20. The tumor necrosis factor receptor superfamily (TNFRSF) plays a vital role in eliciting immune responses against infections. The tree shrew, closely related to primates, is often utilized in human disease mode...

    Authors: Zongjian Huang, Nan Shi, Zhenqiu Luo, Fangfang Chen, Xunwei Feng, Yongjing Lai, Jian Li, Xiang Yi, Wei Xia and Anzhou Tang
    Citation: BMC Genomics 2025 26:338
    Content type: Research Published on:

  21. The poultry immune system is essential for protecting against infectious diseases and maintaining health and productivity. Cell-mediated immune responses (CMIs) protect organisms against intracellular pathogen...

    Authors: Somayeh Kianpoor, Alireza Ehsani, Rasoul Vaez Torshizi, Ali Akbar Masoudi and Mohammad Reza Bakhtiarizadeh
    Citation: BMC Genomics 2025 26:337
    Content type: Research Published on:

  23. Cucurbita pepo L. cultivars display high morphological traits variation. In addition, C. pepo faces numerous threats, such as viral and fungal infections, which significantly influence crop cultivation. Recent ge...

    Authors: C. Pérez-Moro, D. D’Esposito, C. Capuozzo, A. Guadagno, A. Pérez-de-Castro and M. R. Ercolano
    Citation: BMC Genomics 2025 26:335
    Content type: Research Published on:

  24. Leptosphaeria maculans is the causal agent of blackleg, a globally important disease of canola. Investigating the genetic diversity and structure of L. maculans populations can provide insight into its evolutiona...

    Authors: Huibrecht Maria Schreuder, Beatrix Coetzee, Gerhardus Johannes van Coller and Diane Mostert
    Citation: BMC Genomics 2025 26:334
    Content type: Research Published on:

  25. Elaeagnus mollis Diels, is a rare and endangered woody plant endemic to China, which is listed on the IUCN Red List. In the natural state, the viability of its seeds declines very rapidly, which is the key to its...

    Authors: Ren Ruifen, Guo Jiayi, Ji Zhe, Du Shuhui and Yang Xiuyun
    Citation: BMC Genomics 2025 26:333
    Content type: Research Published on:

  26. Pseudostellaria heterophylla (Miq.) Pax ex Pax et Hoffm. is a member of the Caryophyllaceae family, in which dried tuberous root is the well-known traditional Chinese medicine (TCM) and a widespread food ingredie...

    Authors: Chunfeng Huang, Xiaoai Wang, Yanping Gao, Xue Jiang, Lingling Wang, Xiaohong Ou, Yanhong Wang, Tao Zhou and Qing-Song Yuan
    Citation: BMC Genomics 2025 26:332
    Content type: Research Published on:

  27. Alport syndrome is a progressive and hereditary nephropathy characterized by hematuria and proteinuria as well as extra renal manifestations as hearing loss and eye abnormalities. The disease can be expressed ...

    Authors: Washington Candeia de Araújo, Raul Maia Falcão, Raquel Araujo Costa Uchoa, Carlos Alexandre Garcia, Arthur Quintiliano Bezerra da Silva, Kesia Larissa Medeiros Quirino, Francisco Paulo Freire-Neto, Genilson Pereira Gurgel, Paulo Ricardo Porfirio Nascimento, Leonardo Capistrano Ferreira, Priya Duggal, Jorge Estefano S. de Souza and Selma M. B. Jeronimo
    Citation: BMC Genomics 2025 26:331
    Content type: Research Published on:

  28. Muscle development is a key factor influencing the growth performance of piglets. Optimizing this developmental process is crucial for enhancing breeding efficiency and economic profitability. Tryptophan (Trp)...

    Authors: Tianle He, Qingyun Chen, Huifeng Li, Jiani Mao, Ju Luo, Dengjun Ma and Zhenguo Yang
    Citation: BMC Genomics 2025 26:330
    Content type: Research Published on:

  29. While the association between caregiver-child interaction and early childhood development (ECD) has been observed, the underlying biological mechanism remains to be elucidated.

    Authors: Mengna Wei, Rui Chang, Chunan Li, Yanfen Jiang and Jianduan Zhang
    Citation: BMC Genomics 2025 26:329
    Content type: Research Published on:

  30. Lonicera japonica and L. macranthoides are popular medicinal plants used for treating various diseases. Recently, new chromosome level genomes of Lonicera have provided a huge resource for understanding gene func...

    Authors: Jingjie Zhang, Bingbing Pan, Jiangxin Yang, Qi Pan, Panpan Zhu, Jiaotong Yang, Mian Zhang and Qiaoqiao Xiao
    Citation: BMC Genomics 2025 26:328
    Content type: Research Published on:

  31. Fungal plant disease outbreaks are increasing in both scale and frequency, posing severe threats to agroecosystem stability, native biodiversity and food security. Among these, the notorious wheat stem rust fu...

    Authors: Loizos Savva, Anthony Bryan, Dominik Vinopal, Oscar E. Gonzalez-Navarro, Zennah Kosgey, Kimani Cyrus Ndung’u, Jemal Tola Horo, Kitessa Gutu Danu, Messele Molla, Yoseph Alemayehu, David P. Hodson and Diane G.O. Saunders
    Citation: BMC Genomics 2025 26:327
    Content type: Research Published on:

  32. Research on the effects of exogenous glucocorticoids on brown adipose tissue (BAT) is crucial for understanding how these hormones can induce metabolic disorders such as obesity. In this study, we explored the...

    Authors: Xiaoqin Tang, Beibei Zhang, Puhang Xie, Yanpei Wei, Yanbo Qiu, Xiaohua Yi, Ziru Zhang, Muzi She, Xiuzhu Sun and Shuhui Wang
    Citation: BMC Genomics 2025 26:326
    Content type: Research Published on:

  33. In the domestic cat (Felis catus), the corpus luteum (CL) is the main source of progestogen during pregnancy. Here, we studied gene expression changes in different life cycle stages of the CL of pseudopregnant ca...

    Authors: Beate C. Braun, Michał M. Hryciuk and Dorina Meneghini
    Citation: BMC Genomics 2025 26:325
    Content type: Research Published on:

  34. On the one hand, Armillaria is regarded as a plant disease that causes serious root rot of forest trees, on the other hand, Armillaria is also an important symbiotic fungi of the valuable Chinese herb Gastrodia

    Authors: Cheng-Ying Luo, Yao Lu, Lei Su, Jia-Jia Liu, Jia-Yun Miao, Yi-Cen Lin and Lian-Bing Lin
    Citation: BMC Genomics 2025 26:324
    Content type: Research Published on:

  35. Alfalfa (Medicago sativa L.) serves as a vital high-quality forage resource, especially in tropical and subtropical regions where there is a deficiency of protein-rich feed. The red pigmentation of stem of space ...

    Authors: Yaqian Zong, Zhili Zhao, Kai Zhou, Xinhui Duan, Bo Han, Chenggang He, Heping Huang and Hua Jiang
    Citation: BMC Genomics 2025 26:323
    Content type: Research Published on:

  36. The resistance of ESBLs-producing Kp to various groups of antibiotics commonly used against infections they caused had become a global threat and required urgent attention. This study assessed the extended spe...

    Authors: Salawudeen Adamu, Mika’ila Bawa Ali, Mohd Nasir Mohd Desa, Hui-min Neoh, Siti Norbaya Masri, Narcisse Joseph and Tengku Zetty Maztura Tengku Jamaluddin
    Citation: BMC Genomics 2025 26:322
    Content type: Research Published on:

  37. β-galactosidase (BGAL), which is an important cell wall-degrading enzyme, participates in various biological processes, but its effects on pollen tube growth (PTG) remain unclear.

    Authors: Yusheng Xu, Lan Xu, Mingliang Zhang, Hao Wang, Yuqian Wang, Xueping Zhang, Kaijing Zhang, Yihu Sui, Jingjing Qian, Shuangshuang Jia, Ming Qian and Guangrong Cui
    Citation: BMC Genomics 2025 26:321
    Content type: Research Published on:

  38. Authors: Mahamadi Kientega, Ioanna Morianou, Nouhoun Traoré, Nace Kranjc, Honorine Kaboré, Odette N Zongo, Abdoul-Azize Millogo, Patric Stephane Epopa, Franck A. Yao, Adrien M G Belem, Austin Burt and Abdoulaye Diabaté
    Citation: BMC Genomics 2025 26:320
    Content type: Correction Published on:

    The original article was published in BMC Genomics 2024 25:1207

  39. Bacillus is used as a biological control agent in agricultural production. The main mechanisms responsible for its biocontrol activity encompass the generation of various antifungal active substances during life ...

    Authors: Xiaowei Li, Yahan Chen, Shunyi Yang, Yi Zhou and Chengde Yang
    Citation: BMC Genomics 2025 26:319
    Content type: Research Published on:

  40. The main issue of the Klebsiella pneumoniae species complex (KpSC) research in clinical settings is the accurate identification and differentiation of the closely related species within this complex. Moreover, th...

    Authors: Weiyan Jiang, Yanhui Chen, Meimei Lai, Yongan Ji, Suzhen Lin, Jiao Shao and Xiaojian Chen
    Citation: BMC Genomics 2025 26:318
    Content type: Research Published on:

  41. 20-Hydroxyecdysone (20E) is an important hormone that regulates insect development and metamorphosis. The fat body of insects plays a crucial role in nutrient storage and energy metabolism and is considered th...

    Authors: Huili Qiao, Ziqian Tong, Yuanzhuo Wang, Juanjuan Yang, Yanyan Sun, Huixuan Shi, Zhuo Liu, Jianping Duan, Dandan Li and Yunchao Kan
    Citation: BMC Genomics 2025 26:317
    Content type: Research Published on:

  42. Ding’an (DA) pig, a native Chinese breed, is renowned for its excellent meat quality, disease resistance, high reproductive performance, and adaptability. Its meat quality traits hold significant economic valu...

    Authors: Ziyi Wang, Deyou Pan, Xinfeng Xie, Ziqi Zhong, Feng Wang and Qian Xiao
    Citation: BMC Genomics 2025 26:316
    Content type: Research Published on:

  43. Cinnamoyl-CoA reductase (CCR) is the first important and committed enzyme in the monolignol synthesis branch of the lignin biosynthesis (LB) pathway, catalyzing the conversion of cinnamoyl-CoAs to cinnamaldehy...

    Authors: Xixia Song, Dandan Liu, Yubo Yao, Lili Tang, Lili Cheng, Lie Yang, Zhongjuan Jiang, Qinghua Kang, Si Chen, Jiarong Ru, Lili Zhang, Guangwen Wu and Hongmei Yuan
    Citation: BMC Genomics 2025 26:315
    Content type: Research Published on:

  44. The Orobanchaceae family is widely recognized as an exemplary model system for examining the evolutionary dynamics of parasitic plants. However, reports on the mitochondrial genome (mitogenome) of the hemipara...

    Authors: Yang Ma, Jordi López-Pujol, Dongqing Yan, Zekun Deng, Zhen Zhou and Jianming Niu
    Citation: BMC Genomics 2025 26:314
    Content type: Research Published on:

  45. Feed efficiency (FE) is an essential trait in livestock species because of the constant demand to increase the productivity and sustainability of livestock production systems. A better understanding of the bio...

    Authors: Pablo Augusto de Souza Fonseca, Aroa Suarez-Vega, Cristina Esteban-Blanco, Héctor Marina, Rocío Pelayo, Beatriz Gutiérrez-Gil and Juan-José Arranz
    Citation: BMC Genomics 2025 26:313
    Content type: Research Published on:

  46. Salt stress is one of the major limiting factors of Leymus chinensis (named sheepgrass) growth, which accelerates inhibitive effects that are particularly concomitant with low light regimes (LL-Salt). However, li...

    Authors: Jikai Li, Suyang Fang, Hailing Zhang, Zubair Iqbal, Chen Shang, Weibo Han, Kai Huang, Xiangshen Meng, Muyuan Dai, Zhiheng Lu, Bingnan Guo and Mingnan Qu
    Citation: BMC Genomics 2025 26:312
    Content type: Research Published on:

  47. Phytophthora blight is a highly destructive soil-borne disease caused by Phytophthora capsici Leonian, which threatens pepper production. The molecular mechanism of pepper resistance to phytophthora blight is unc...

    Authors: Fengyan Shi, Xiuxue Wang, Meijun Wei, Xi Zhang, Zhidan Wang, Xiaochun Lu and Chunlei Zou
    Citation: BMC Genomics 2025 26:311
    Content type: Research Published on:

  48. Improving reproductive performance in Yorkshire pigs, a key maternal line in three-way crossbreeding systems, remains challenging due to low heritability and historical selection pressures favoring production ...

    Authors: Ran Wei, Zhenyang Zhang, He Han, Jian Miao, Pengfei Yu, Hong Cheng, Wei Zhao, Xiaoliang Hou, Jianlan Wang, Yongqi He, Yan Fu, Zhen Wang, Qishan Wang, Zhe Zhang and Yuchun Pan
    Citation: BMC Genomics 2025 26:310
    Content type: Research Published on:

  49. The 14–3-3 proteins are highly conserved regulatory eukaryotic proteins, which are crucial in growth, development, and stress responses. However, systematic characterization of the 14–3-3 gene family in Brassicac...

    Authors: Jingya Zhao, Shengqin Liu, Hui Ren, Owusu Edwin Afriyie, Mengzhu Zhang, Dachao Xu and Xianzhong Huang
    Citation: BMC Genomics 2025 26:309
    Content type: Research Published on:

  50. Aromatase, encoded by Cyp19a1, is the rate limiting enzyme in biosynthesis of estrogens, and excessive aromatase can reduce the semen quality in roosters. Seminal plasma extracellular vesicles (SPEV) are nanoscal...

    Authors: Xuliang Luo, Yan Guo, Xuelian Li, Zi Mei, Haobo Zhou, Ping Qiu, Haoxin Wang, Yan Chen and Yanzhang Gong
    Citation: BMC Genomics 2025 26:305
    Content type: Research Published on:

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BMC Genomics

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