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  1. Ionizing radiation (IR) is an abiotic stress factor that can be not only a means to explore plant resistance but also a potent mutagen in agricultural breeding. The diverse physical parameters of different typ...

    Authors: Jianing Ding, Chaoli Xu, Yan Du, Xiao Liu, Jingmin Chen, Zhe Li, Jing Long, Yukun Sheng, Wenjie Jin, Dan Xu and Libin Zhou
    Citation: BMC Genomics 2025 26:308
  2. The ixodid tick Haemaphysalis longicornis Neumann, commonly referred to as the Asian longhorned tick, has expanded its range outside of East Asia into countries such as Australia, New Zealand, and the United Stat...

    Authors: Mohamed Abdallah Mohamed Moustafa, Miranda M. Barnes, Nicole E. Wagner, Deanna Bodine, Kylie Bendele, Pete D. Teel, Perot Saelao and Dana C. Price
    Citation: BMC Genomics 2025 26:307
  3. Sorghum is a vital cereal crop for over 750 million people, ranking 5th globally. It has multiple purposes, including food, feed, and biofuels, and is essential in Ethiopia, which has a rich genetic diversity ...

    Authors: Addisu Getahun, Admas Alemu, Habte Nida and Adugna Abdi Woldesemayat
    Citation: BMC Genomics 2025 26:304
  4. The hypothalamus is a critical organ that regulates sexual development in animals. However, current research on the hypothalamic regulation of sexual maturation in female goats remains limited. In this study, ...

    Authors: Qing Li, Tianle Chao, Yanyan Wang, Peipei He, Lu Zhang and Jianmin Wang
    Citation: BMC Genomics 2025 26:303
  5. Acute myeloid leukemia (AML) is the most common type of acute leukemia, accounting for 20% of cases in children and adolescents. Genome-wide studies have identified genes that are commonly mutated in AML, incl...

    Authors: Elise Georges, William Ho, Miren Urrutia Iturritza, Lel Eory, Kamila Malysz, Ulduz Sobhiafshar, Alan L. Archibald, Daniel J. Macqueen, Barbara Shih, David Garrick and Douglas Vernimmen
    Citation: BMC Genomics 2025 26:300
  6. Understanding the mechanisms of genetic evolution in marine yeasts is essential for their ecological and biotechnological applications. Scheffersomyces spartinae, an ascomycetous yeast species, characterized by i...

    Authors: Yu-Ting Bai, Awkash Sharma, Qian Xiang, Li-Yan Tian, Ke-Jing Li, Bao-Ying Guo, Lei Qi and Dao-Qiong Zheng
    Citation: BMC Genomics 2025 26:297
  7. The development of skeletal muscles is intricately modulated by multiple genetic factors and significantly impacts the economic value of meat rabbits. However, our knowledge of epigenetics in rabbit skeletal m...

    Authors: Kun Du, Dai-hua Wang, Shen-qiang Hu, Yu Xia, Qian Wu, Mao-qing Gu and Xi-wen Chen
    Citation: BMC Genomics 2025 26:296
  8. Roseobacteraceae, often referred to as the marine roseobacter clade (MRC), are pivotal constituents of bacterial communities in coastal and pelagic marine environments. During the past two decades, 75 roseophage...

    Authors: Xingyu Huang, Chen Yu and Longfei Lu
    Citation: BMC Genomics 2025 26:295
  9. The Atlantic salmon (Salmo salar) aquaculture industry must mitigate the impacts of rising ocean temperatures and the increased prevalence/severity of marine heat waves. Therefore, we investigated the genetic arc...

    Authors: Eric H. Ignatz, Melissa S. Allen, Jennifer R. Hall, Rebeccah M. Sandrelli, Mark D. Fast, Guy M. L. Perry, Matthew L. Rise and A. Kurt Gamperl
    Citation: BMC Genomics 2025 26:294
  10. Cavefish exhibit significant morphological changes that result in trade-offs in metabolic requirements and energy utilization in perpetual darkness. As cellular “powerhouses”, mitochondria play crucial roles i...

    Authors: Shuang Song, Jianhan Cao, Hongmei Xiang, Zhixiao Liu and Wansheng Jiang
    Citation: BMC Genomics 2025 26:293
  11. Genetic diversity in livestock and poultry is critical for adapting production systems to future challenges. However, inadequate management practices, particularly in developing countries, have led to the exti...

    Authors: Jiale Han, Hanrui Shao, Minhao Sun, Feng Gao, Qiaoyan Hu, Ge Yang, Halima Jafari, Na Li and Ruihua Dang
    Citation: BMC Genomics 2025 26:292
  12. Previous studies have reported several genetic loci associated with lung function. However, the mediating mechanism between these genetic loci and lung function phenotype is rarely explored. In this research, ...

    Authors: Shisheng Peng, Jinlong Fang, Weiliang Mo, Guodong Hu and Senquan Wu
    Citation: BMC Genomics 2025 26:289
  13. Marfan syndrome (MFS) is an inherited autosomal dominant disorder that affects connective tissue with an incidence of about 1 in 5,000 to 10,000 people. 90% of MFS is caused by mutations in the fibrillin-1 (FBN1)...

    Authors: Shitong Huang, Jiansong Chen, Qiuyu Wang, Ruyue Zhang, Jian Zhuang, Ruiyuan Huang, Changjiang Yu, Miaoxian Fang, Haishan Zhao and Liming Lei
    Citation: BMC Genomics 2025 26:288
  14. The Syrian hamster (Mesocricetus auratus) has shown promise as a human diseases model, recapitulating features of different human diseases including COVID-19. However, the landscape of its genome and transcriptom...

    Authors: Chuchu Wang, Zhenguo Cheng, Jinxin Miao, Xia Xue, Yunshu Dong, Li Zhao, Haoran Guo, Jianyao Wang, Zhizhong Wang, Shuangshuang Lu, Guangming Fang, Ying Peng, Yafei Zhai, Zhongxian Zhang, Dongling Gao, Zhimin Wang…
    Citation: BMC Genomics 2025 26:286
  15. Copy number variations (CNVs) represent a common and highly specific type of variation in the genome, potentially influencing genetic diversity and mammalian phenotypic development. Structural variants, such a...

    Authors: Jan Berghöfer, Nadia Khaveh, Stefan Mundlos and Julia Metzger
    Citation: BMC Genomics 2025 26:285
  16. Improving photosynthetic efficiency is an essential strategy for advancing wheat breeding progress. Integrating wheat genetic resources provides an opportunity to discover pivotal genomic regions and candidate...

    Authors: Ming Chen, Tao Chen, Letong Yun, Zhuo Che, Jingfu Ma, Binxue Kong, Jiangying Long, Chunhua Cheng, Kaiqi Guo, Peipei Zhang, Lijian Guo and Delong Yang
    Citation: BMC Genomics 2025 26:284
  17. Adzuki bean (Vigna angularis) rust, caused by the fungus Uromyces vignae, is an important disease affecting adzuki bean yield and quality. Previously, several NAC transcription factors (TFs) were induced by rust ...

    Authors: Liu Shengmiao, Ding Xin, Li Yue, Yin Lihua, Ke Xiwang and Zuo Yuhu
    Citation: BMC Genomics 2025 26:283
  18. A comprehensive understanding of the molecular differences between X and Y sperm in Holstein bull semen is crucial for advancing sex control technologies. While previous studies have primarily focused on prote...

    Authors: Aishao Shangguan, Fengling Ding, Rui Ding, Wei Sun, Xihe Li, Xiangnan Bao, Tiezhu Zhang, Huihui Chi, Qi Xiong, Mingxin Chen, Yang Zhou and Shujun Zhang
    Citation: BMC Genomics 2025 26:282
  19. A considerable proportion of males suffer from asymptomatic SARS-CoV-2 infection, while the effect on reproductive function and underlying pathomechanisms remain unclear.

    Authors: Jialyu Huang, Yufang Su, Jiawei Wang, Zheng Fang, Yiwei Zhang, Hong Chen, Xinxia Wan, Yuanhuan Xiong, Ning Song, Houyang Chen and Xingwu Wu
    Citation: BMC Genomics 2025 26:281
  20. In hybrid rice seed production, rice varieties with a small flag leaf angle (FLA) experience obstacles to cross-pollination at the early heading stage, and farmers usually need to remove flag leaves to achieve...

    Authors: Tianhu Li, Zhen Yang, Yang Ang, Yingying Zhao, Yanan Zhang, Zhengbo Liu, Hao Sun, Yinping Chang, Mingyu Du, Xianping Cheng, Jinghan Sun and Erbao Liu
    Citation: BMC Genomics 2025 26:280
  21. Porcine reproductive and respiratory syndrome virus (PRRSV) can be transmitted across the maternal-fetal-interface from an infected gilt to her fetuses. Although fetal infection status and disease outcomes var...

    Authors: Angelica Van Goor, Alex Pasternak, Kristen E. Walker, Shannon Chick, John C. S. Harding and Joan K. Lunney
    Citation: BMC Genomics 2025 26:279
  22. Although it has been demonstrated that gastrointestinal microorganisms greatly influence livestock performance, the effect of gastrointestinal microorganisms on the growth performance of crossbred cattle remai...

    Authors: Wei Zhao, Lina Ma, Lin Xue, Qiufei Jiang, Yuan Feng, Suwan Wang, Jinli Tian, Xiaohua Tian, Yaling Gu and Juan Zhang
    Citation: BMC Genomics 2025 26:278
  23. Soybean is an important legume crop and has significant agricultural and economic value. P4-ATPases (aminophospholipid ATPases, ALAs), one of the classes of P-type ATPases, can transport or flip phospholipids ...

    Authors: Jingjing Wei, Gaoyang Zhang, Huanhuan Lv, Saidi Wang, Xingyu Liu, Yanli Qi, Zhongke Sun and Chengwei Li
    Citation: BMC Genomics 2025 26:277
  24. Taraxacum mongolicum is rich in phenolic acids and is widely utilized in food and medicine globally. Our previous research demonstrated that the abscisic acid (ABA) hormone significantly enhances chicoric acid ac...

    Authors: Qun Liu, Zhiqing Wu, Changyang Yu, Xiwu Qi, Hailing Fang, Xu Yu, Li Li, Yang Bai, Dongmei Liu, Zequn Chen, Guoyin Kai and Chengyuan Liang
    Citation: BMC Genomics 2025 26:276
  25. DNA methylation influences gene expression and is involved in numerous biological processes, including fat production. It is involved in lipid generation in numerous animal species, including poultry. However,...

    Authors: Xiaohuan Chao, Lijin Guo, Meiling Hu, Mao Ye, Zhexia Fan, Kang Luan, Jiahao Chen, Chunlei Zhang, Manqing Liu, Bo Zhou, Xiquan Zhang, Zhenhui Li and Qingbin Luo
    Citation: BMC Genomics 2025 26:275
  26. With the rapid advancement of sequencing technology, the increasing availability of single-cell multi-omics data from the same cells has provided us with unprecedented opportunities to understand the cellular ...

    Authors: Bai Zhang, Mengdi Nan, Liugen Wang, Hanwen Wu, Xiang Chen, Yongle Shi, Yibing Ma and Jie Gao
    Citation: BMC Genomics 2025 26:274
  27. Trehalose-6-phosphate synthase (TPS) is an essential enzyme involved in the production of trehalose, and the genes associated with TPS are crucial for various processes such as growth, development, defense mechan...

    Authors: Zaibao Zhang, Tao Xiong, Kejia Li, Kexin Huang, Chunxia Liao and Guangqu Liu
    Citation: BMC Genomics 2025 26:273
  28. Brown adipose tissue (BAT) has a significant impact in newborn goats on maintaining body temperature through non-shivering thermogenesis in response to cold exposure. However, the roles of heat treatment on BA...

    Authors: Yulong Song, Die Li, Duo Su, Tingting Jiang, Longrui Li, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Jiaxue Cao, Li Li, Hongping Zhang and Linjie Wang
    Citation: BMC Genomics 2025 26:272
  29. Fatty acid hydroxylases (FAHs) are a family of enzymes that includes fatty acid hydroxylases, carotenoid hydroxylases, and sterol desaturases. Fatty acids are highly important for plants. They are the main sou...

    Authors: Haijing Gu, Wenxiang Feng, Teame Gereziher Mehari, Yifan Wang, Ziyin Wang, Yifan Xu, Yizhou Zhao, Junfeng Tang, Ke Zhang, Zitong Zhou, Wei Wang, Ruqin Zhou, Jianyong Wu and Baohua Wang
    Citation: BMC Genomics 2025 26:271
  30. Oocyte maturation is crucial for female fertility and embryonic development, encompassing nuclear and cytoplasmic maturation. Supportive cells of follicles, such as granulosa cells, are essential for oocyte gr...

    Authors: Yibo Wang, Yichuan Zhang, Tianjie Li, Yun Ren, Ping Zhou, Lin Fu, Chenxi Xiao, Ziying Huang, Hanji Huang, Wenfeng Xie, Yuxin Luo, Yanan Qi, Hongcui Zhao, Yang Yu, Yong Fan and Heng Pan
    Citation: BMC Genomics 2025 26:270
  31. The occurrence and development of colorectal cancer (CRC) is an incredibly long process that involves continuous changes in the tumor microenvironment. These constant changes may ultimately result in genetic a...

    Authors: Hao Yang, Yu Gan, Shenghai Jiang, Xianchang Zhu, Yang Xia, Dengmei Gong, Xianrang Xie, Yao Gong, Yi Zhang, Qian Lei, Maijian Wang and Jida Li
    Citation: BMC Genomics 2025 26:269
  32. Ducks are globally important poultry species and a major source of farm animal products, including meat, eggs, and feathers. A thorough understanding of the functional genomic and transcriptomic sequences is c...

    Authors: Qiuyu Tao, Anqi Huang, Jingjing Qi, Zhao Yang, Shihao Guo, Yinjuan Lu, Xinxin He, Xu Han, Shuaixue Jiang, Mengru Xu, Yuan Bai, Tao Zhang, Shenqiang Hu, Liang Li, Lili Bai and HeHe Liu
    Citation: BMC Genomics 2025 26:268
  33. Runs of Homozygosity (ROH) are homozygous genomic fragments inherited from parents to offspring. ROH can be used to indicate the level of inbreeding, as well as to identify possible signatures of artificial or...

    Authors: Zhi-peng Han, Lu-lu Zhang, Xiao-peng Li, Li-jun Zhu, Xue-chen Zhang, Wen Zhou and Shudong Liu
    Citation: BMC Genomics 2025 26:267
  34. The complete dormancy release determines the quality of bud break, flowering and fruiting. While in tree peony (Paeonia suffruticosa Andr.), the insufficient accumulation of cold temperatures results in incomplet...

    Authors: Qianqian Wang, Bole Li, Zefeng Qiu, Jiayi Ying, Xuyichen Jin, Zeyun Lu, Junli Zhang, Xia Chen and Xiangtao Zhu
    Citation: BMC Genomics 2025 26:266
  35. Understanding the mechanisms of early clearance of Mycobacterium tuberculosis (Mtb) may illuminate new therapeutic strategies for tuberculosis (TB). We previously found genetic, epigenetic, and transcriptomic sig...

    Authors: Madison S. Cox, Kimberly A. Dill-McFarland, Jason D. Simmons, Penelope Benchek, Harriet Mayanja-Kizza, W. Henry Boom, Catherine M. Stein and Thomas R. Hawn
    Citation: BMC Genomics 2025 26:265
  36. Transcription factors (TFs) regulate the genes’ expression by binding to DNA sequences. Aligned TFBSs of the same TF are seen as cis-regulatory motifs, and substantial computational efforts have been invested ...

    Authors: Shuangquan Zhang, Anjun Ma, Xuping Xie, Zhichao Lian and Yan Wang
    Citation: BMC Genomics 2025 26(Suppl 2):264

    This article is part of a Supplement: Volume 26 Supplement 2

  37. Linked-reads improve de novo assembly, haplotype phasing, structural variant (SV) detection, and other applications through highly-multiplexed genome partitioning and barcoding. Whole genome assembly and assem...

    Authors: Can Luo, Brock A. Peters and Xin Maizie Zhou
    Citation: BMC Genomics 2025 26(Suppl 2):263

    This article is part of a Supplement: Volume 26 Supplement 2

  38. Sepia esculenta is one of the most abundant extant squid populations in Southeast Asia and is of interest due to its rapid reproductive rate and high commercial value. In recent years, with the rapid development ...

    Authors: Yancheng Zhao, Deyuan Chang, Yanxuan Zheng, Yuwei Zhang, Yongjie Wang, Xiaokai Bao, Guohua Sun, Yanwei Feng, Zan Li, Xiumei Liu and Jianmin Yang
    Citation: BMC Genomics 2025 26:262
  39. Authors: Linnea K. Andersen, Neil F. Thompson, Jason W. Abernathy, Ridwan O. Ahmed, Ali Ali, Rafet Al-Tobasei, Benjamin H. Beck, Bernarda Calla, Thomas A. Delomas, Rex A. Dunham, Christine G. Elsik, S. Adam Fuller, Julio C. García, Mackenzie R. Gavery, Christopher M. Hollenbeck, Kevin M. Johnson…
    Citation: BMC Genomics 2025 26:260

    The original article was published in BMC Genomics 2025 26:155

  40. Utilizing Single Nucleotide Polymorphism (SNP) marker technology, a phylogenetic and agronomic trait network analysis was conducted on the collected hot pepper and sweet pepper germplasm resources, providing a...

    Authors: Yaning Meng, Hongxiao Zhang, Zhe Zhang, Xinxin Li, Zhanghong Yu, Yanqin Fan and Libin Yan
    Citation: BMC Genomics 2025 26:258
  41. Eimeria are obligate protozoan parasites, and more than 1,500 species have been reported. However, Eimeria genomes lag behind many other eukaryotes since obtaining many oocysts is difficult due to a lack of susta...

    Authors: Kaihui Zhang, Yudong Cai, Yuancai Chen, Yin Fu, Ziqi Zhu, Jianying Huang, Huikai Qin, Qimeng Yang, Xinmei Li, Yayun Wu, Xun Suo, Yu Jiang and Longxian Zhang
    Citation: BMC Genomics 2025 26:257
  42. Single nucleotide polymorphisms (SNPs) have emerged as the marker of choice in breeding and genetics, particularly in non-model organisms such as black pepper (Piper nigrum L.), a globally recognized spice crop. ...

    Authors: Hiruni A. Thanthirige, Nilni A. Wimalarathna and Anushka M. Wickramasuriya
    Citation: BMC Genomics 2025 26:256

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